• Immunofluorescence analysis of mouse spleen using FCGR2A Rabbit polyclonal antibody (STJ23641) at dilution of 1:100 (40x lens). Blue: DAPI for nuclear staining.
  • Western blot analysis of extracts of various cell lines, using FCGR2A antibody (STJ23641) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 90s.

Anti-FCGR2A antibody (34-316) (STJ23641)

SKU:
STJ23641

£112.50 - £522.50
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Host: Rabbit
Applications: WB/IF
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-FCGR2A (34-316) is suitable for use in Western Blot and Immunofluorescence research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.05% Proclin300, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:1000
IF/ICC 1:50-1:200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: FCGR2A
Gene ID: 2212
Uniprot ID: FCG2A_HUMAN
Immunogen Region: 34-316
Immunogen: A synthetic peptide corresponding to a sequence within amino acids 34-316 of human FCGR2A (NP_001129691.1).
Immunogen Sequence: QAAAPPKAVLKLEPPWINVL QEDSVTLTCQGARSPESDSI QWFHNGNLIPTHTQPSYRFK ANNNDSGEYTCQTGQTSLSD PVHLTVLSEWLVLQTPHLEF QEGETIMLRCHSWKDKPLVK VTFFQNGKSQKFSHLDPTFS IPQANHSHSGDYHCTGNIGY TLFSSKPVTITVQVPSMGSS SPMGIIVAVVIATAVAAIVA AVVALIYCRKKRISANSTDP VKAAQFEPPGRQMIAIRKR
Tissue Specificity Found on monocytes, neutrophils and eosinophil platelets.
Post Translational Modifications Phosphorylated by SRC-type Tyr-kinases such as LYN, BLK, FYN, HCK and SYK.
Function Binds to the Fc region of immunoglobulins gamma. Low affinity receptor. By binding to IgG it initiates cellular responses against pathogens and soluble antigens. Promotes phagocytosis of opsonized antigens.
Protein Name Low Affinity Immunoglobulin Gamma Fc Region Receptor Ii-A
Igg Fc Receptor Ii-A
Cdw32
Fc-Gamma Rii-A
Fc-Gamma-Riia
Fcrii-A
Cd Antigen Cd32
Database Links Reactome: R-HSA-2029481
Reactome: R-HSA-2029482
Reactome: R-HSA-2029485
Reactome: R-HSA-6798695
Reactome: R-HSA-9664323
Cellular Localisation Cell Membrane
Single-Pass Type I Membrane Protein
Alternative Antibody Names Anti-Low Affinity Immunoglobulin Gamma Fc Region Receptor Ii-A antibody
Anti-Igg Fc Receptor Ii-A antibody
Anti-Cdw32 antibody
Anti-Fc-Gamma Rii-A antibody
Anti-Fc-Gamma-Riia antibody
Anti-Fcrii-A antibody
Anti-Cd Antigen Cd32 antibody
Anti-FCGR2A antibody
Anti-CD32 antibody
Anti-FCG2 antibody
Anti-FCGR2A1 antibody
Anti-IGFR2 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance