• Immunofluorescence analysis of THP-1 cells using CD64 Rabbit polyclonal antibody (STJ23640) at dilution of 1:100 (40x lens). Blue: DAPI for nuclear staining.
  • Western blot analysis of extracts of various cell lines, using CD64 antibody (STJ23640) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 90s.

Anti-FCGR1A antibody (16-288) (STJ23640)

SKU:
STJ23640

£169.50 - £449.50
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Host: Rabbit
Applications: WB/IF
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-FCGR1A (16-288) is suitable for use in Western Blot and Immunofluorescence research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.05% Proclin300, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:1000
IF/ICC 1:50-1:200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: FCGR1A
Gene ID: 2209
Uniprot ID: FCGR1_HUMAN
Immunogen Region: 16-288
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 16-288 of human CD64 (NP_000557.1).
Immunogen Sequence: QVDTTKAVITLQPPWVSVFQ EETVTLHCEVLHLPGSSSTQ WFLNGTATQTSTPSYRITSA SVNDSGEYRCQRGLSGRSDP IQLEIHRGWLLLQVSSRVFT EGEPLALRCHAWKDKLVYNV LYYRNGKAFKFFHWNSNLTI LKTNISHNGTYHCSGMGKHR YTSAGISVTVKELFPAPVLN ASVTSPLLEGNLVTLSCETK LLLQRPGLQLYFSFYMGSKT LRGRNTSSEYQILTARRED
Tissue Specificity Monocyte/macrophage specific.
Post Translational Modifications Phosphorylated on serine residues.
Function High affinity receptor for the Fc region of immunoglobulins gamma. Functions in both innate and adaptive immune responses. Mediates IgG effector functions on monocytes triggering antibody-dependent cellular cytotoxicity (ADCC) of virus-infected cells.
Protein Name High Affinity Immunoglobulin Gamma Fc Receptor I
Igg Fc Receptor I
Fc-Gamma Ri
Fcri
Fc-Gamma Ria
Fcgammaria
Cd Antigen Cd64
Database Links Reactome: R-HSA-1236978
Reactome: R-HSA-198933
Reactome: R-HSA-2029481
Reactome: R-HSA-2029482
Reactome: R-HSA-2029485
Reactome: R-HSA-877300
Reactome: R-HSA-9664323
Cellular Localisation Cell Membrane
Single-Pass Type I Membrane Protein
Stabilized At The Cell Membrane Through Interaction With Fcer1g
Alternative Antibody Names Anti-High Affinity Immunoglobulin Gamma Fc Receptor I antibody
Anti-Igg Fc Receptor I antibody
Anti-Fc-Gamma Ri antibody
Anti-Fcri antibody
Anti-Fc-Gamma Ria antibody
Anti-Fcgammaria antibody
Anti-Cd Antigen Cd64 antibody
Anti-FCGR1A antibody
Anti-FCG1 antibody
Anti-FCGR1 antibody
Anti-IGFR1 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance