Host: |
Rabbit |
Applications: |
WB/IF |
Reactivity: |
Mouse/Rat |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit polyclonal antibody anti-FBP2 (1-339) is suitable for use in Western Blot and Immunofluorescence research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
Purification: |
Affinity purification |
Dilution Range: |
WB 1:500-1:2000IF/ICC 1:50-1:200 |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
FBP2 |
Gene ID: |
8789 |
Uniprot ID: |
F16P2_HUMAN |
Immunogen Region: |
1-339 |
Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-339 of human FBP2 (NP_003828.2). |
Immunogen Sequence: |
MTDRSPFETDMLTLTRYVME KGRQAKGTGELTQLLNSMLT AIKAISSAVRKAGLAHLYGI AGSVNVTGDEVKKLDVLSNS LVINMVQSSYSTCVLVSEEN KDAIITAKEKRGKYVVCFDP LDGSSNIDCLASIGTIFAIY RKTSEDEPSEKDALQCGRNI VAAGYALYGSATLVALSTGQ GVDLFMLDPALGEFVLVEKD VKIKKKGKIYSLNEGYAKYF DAATTEYVQKKKFPEDGSA |
Tissue Specificity | Expressed in skeletal muscle (at protein level). |
Function | Catalyzes the hydrolysis of fructose 1,6-bisphosphate to fructose 6-phosphate in the presence of divalent cations and probably participates in glycogen synthesis from carbohydrate precursors, such as lactate. |
Protein Name | Fructose-1 -6-Bisphosphatase Isozyme 2Fbpase 2D-Fructose-1 -6-Bisphosphate 1-Phosphohydrolase 2Muscle Fbpase |
Database Links | Reactome: R-HSA-70263 |
Cellular Localisation | Cell JunctionCytoplasmNucleusMyofibrilSarcomereZ LineIn Neonatal CardiomyocytesDistributed Throughout The CytosolAccumulating In The Intercalated Disks Which Occur At The Z Line Of Cardiomyocytes And Connect Adjacent CellsAnd Also Located In The NucleusDissociates From The Z Line Following An Increase In Cytosolic Ca(2+) ConcentrationIn Muscle Precursor CellsLocalizes Predominantly To The Nucleus And To A Lesser Extent To The Cytoplasm At The Proliferative PhaseWhile Mainly Localizing To The Cytoplasm At The Differentiation PhaseColocalizes With Aldoa And Alpha-Actinin On Both Sides Of The Z Line Of Skeletal MuscleDissociates Rapidly From The Z Line Following An Increase In Cytosolic Ca(2+) Concentration |
Alternative Antibody Names | Anti-Fructose-1 -6-Bisphosphatase Isozyme 2 antibodyAnti-Fbpase 2 antibodyAnti-D-Fructose-1 -6-Bisphosphate 1-Phosphohydrolase 2 antibodyAnti-Muscle Fbpase antibodyAnti-FBP2 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance