• Immunofluorescence analysis of U-2 OS cells using FBP1 Rabbit polyclonal antibody (STJ27359) at dilution of 1:100 (40x lens). Blue: DAPI for nuclear staining.
  • Immunofluorescence analysis of NIH-3T3 cells using FBP1 Rabbit polyclonal antibody (STJ27359) at dilution of 1:100 (40x lens). Blue: DAPI for nuclear staining.
  • Immunofluorescence analysis of C6 cells using FBP1 Rabbit polyclonal antibody (STJ27359) at dilution of 1:100 (40x lens). Blue: DAPI for nuclear staining.
  • Western blot analysis of extracts of various cell lines, using FBP1 antibody (STJ27359) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 1s.

Anti-FBP1 antibody (50-150) (STJ27359)

SKU:
STJ27359

£169.50 - £449.50
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Host: Rabbit
Applications: WB/IF
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-FBP1 (50-150) is suitable for use in Western Blot and Immunofluorescence research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.05% Proclin300, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:1000
IF/ICC 1:50-1:200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: FBP1
Gene ID: 2203
Uniprot ID: F16P1_HUMAN
Immunogen Region: 50-150
Immunogen: A synthetic peptide corresponding to a sequence within amino acids 50-150 of human FBP1 (NP_000498.2).
Immunogen Sequence: RKAGIAHLYGIAGSTNVTGD QVKKLDVLSNDLVMNMLKSS FATCVLVSEEDKHAIIVEPE KRGKYVVCFDPLDGSSNIDC LVSVGTIFGIYRKKSTDEPS E
Tissue Specificity Expressed in pancreatic islets.
Function Catalyzes the hydrolysis of fructose 1,6-bisphosphate to fructose 6-phosphate in the presence of divalent cations, acting as a rate-limiting enzyme in gluconeogenesis. Plays a role in regulating glucose sensing and insulin secretion of pancreatic beta-cells. Appears to modulate glycerol gluconeogenesis in liver. Important regulator of appetite and adiposity.increased expression of the protein in liver after nutrient excess increases circulating satiety hormones and reduces appetite-stimulating neuropeptides and thus seems to provide a feedback mechanism to limit weight gain.
Protein Name Fructose-1 -6-Bisphosphatase 1
Fbpase 1
D-Fructose-1 -6-Bisphosphate 1-Phosphohydrolase 1
Liver Fbpase
Database Links Reactome: R-HSA-70263
Alternative Antibody Names Anti-Fructose-1 -6-Bisphosphatase 1 antibody
Anti-Fbpase 1 antibody
Anti-D-Fructose-1 -6-Bisphosphate 1-Phosphohydrolase 1 antibody
Anti-Liver Fbpase antibody
Anti-FBP1 antibody
Anti-FBP antibody

Information sourced from Uniprot.org

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