Anti-FASTKD1 antibody (638-847) (STJ29521)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal FASTKD1 (638-847) antibody for use in WB and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | FASTKD1 |
| Gene ID | 79675 |
| Uniprot ID | FAKD1_HUMAN |
| Immunogen Region | 638-847 |
| Immunogen Sequence | KFLARLDSQLEILSPSRSAR VQFHLMELNRSVCLECPEFQ IPWFHDRFCQQYNKGIGGMD GTQQQIFKMLAEVLGGINCV KASVLTPYYHKVDFECILDK RKKPLPYGSHNIALGQLPEM PWESNIEIVGSRLPPGAERI ALEFLDSKALCRNIPHMKGK SAMKKRHLEILGYRVIQISQ FEWNSMALSTKDARMDYLRE CIFGEVKSCL |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 638-847 of human FASTKD1 (NP_078898.3). |
Additional Info
| Tissue Specificity | Expression detected in spleen, thymus, testis, ovary, colon, heart, smooth muscle, kidney, brain, lung, liver and white adipose tissue with highest expression in heart. |
| Function | Involved in the down-regulation of mitochondrial MT-ND3 mRNA levels which leads to decreased respiratory complex I abundance and activity. |
| Protein Name | Fast Kinase Domain-Containing Protein 1 - Mitochondrial |
| Database Links | |
| Cellular Localisation | MitochondrionPreferentially Localizes To Mitochondrial Rna GranulesPlatforms For Post-Transcriptional Rna Modification And Ribosome Assembly |
| Alternative Antibody Names | Anti-Fast Kinase Domain-Containing Protein 1 - Mitochondrial antibodyAnti-FASTKD1 antibodyAnti-KIAA1800 antibody |
Information sourced from Uniprot.org