| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-FARP1 (350-550) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
FARP1 |
| Gene ID: |
10160 |
| Uniprot ID: |
FARP1_HUMAN |
| Immunogen Region: |
350-550 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 350-550 of human FARP1 (NP_005757.1). |
| Immunogen Sequence: |
YVKEGGHKKVQFERKHSKIH SIRSLASQPTELNSEVLEQS QQSTSLTFGEGAESPGGQSC RRGKEPKVSAGEPGSHPSPA PRRSPAGNKQADGAASAPTE EEEEVVKDRTQQSKPQPPQP STGSLTGSPHLSELSVNSQG GVAPANVTLSPNLSPDTKQA SPLISPLLNDQACPRTDDED EGRRKRFPTDKAYFIAKEVS T |
| Tissue Specificity | Detected in cAMP-treated chondrocytes, but not in untreated chondrocytes. Detected in fetal brain, heart and spleen, and in adult testis, kidney and lung. |
| Function | Functions as guanine nucleotide exchange factor for RAC1. May play a role in semaphorin signaling. Plays a role in the assembly and disassembly of dendritic filopodia, the formation of dendritic spines, regulation of dendrite length and ultimately the formation of synapses. |
| Protein Name | Ferm - Arhgef And Pleckstrin Domain-Containing Protein 1Chondrocyte-Derived Ezrin-Like ProteinFerm - Rhogef And Pleckstrin Domain-Containing Protein 1Pleckstrin Homology Domain-Containing Family C Member 2Ph Domain-Containing Family C Member 2 |
| Database Links | Reactome: R-HSA-8980692Reactome: R-HSA-9013148Reactome: R-HSA-9013149Reactome: R-HSA-9035034 |
| Cellular Localisation | Cell MembranePeripheral Membrane ProteinCytoplasmic SideSynapseSynaptosomeCytoplasmCytosolCell ProjectionFilopodiumDendriteDendritic SpineRecruited To The Cell Membrane Via Interaction With Cadm1 |
| Alternative Antibody Names | Anti-Ferm - Arhgef And Pleckstrin Domain-Containing Protein 1 antibodyAnti-Chondrocyte-Derived Ezrin-Like Protein antibodyAnti-Ferm - Rhogef And Pleckstrin Domain-Containing Protein 1 antibodyAnti-Pleckstrin Homology Domain-Containing Family C Member 2 antibodyAnti-Ph Domain-Containing Family C Member 2 antibodyAnti-FARP1 antibodyAnti-CDEP antibodyAnti-PLEKHC2 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
