| Tissue Specificity | Detected in cAMP-treated chondrocytes, but not in untreated chondrocytes. Detected in fetal brain, heart and spleen, and in adult testis, kidney and lung. |
| Function | Functions as a guanine nucleotide exchange factor for RAC1. May play a role in semaphorin signaling. Plays a role in the assembly and disassembly of dendritic filopodia, the formation of dendritic spines, regulation of dendrite length and ultimately the formation of synapses. |
| Protein Name | Ferm - Arhgef And Pleckstrin Domain-Containing Protein 1Chondrocyte-Derived Ezrin-Like ProteinFerm - Rhogef And Pleckstrin Domain-Containing Protein 1Pleckstrin Homology Domain-Containing Family C Member 2Ph Domain-Containing Family C Member 2 |
| Database Links | Reactome: R-HSA-8980692Reactome: R-HSA-9013148Reactome: R-HSA-9013149Reactome: R-HSA-9035034 |
| Cellular Localisation | Cell MembranePeripheral Membrane ProteinCytoplasmic SideSynapseSynaptosomeCytoplasmCytosolCell ProjectionFilopodiumDendriteDendritic SpineRecruited To The Cell Membrane Via Interaction With Cadm1 |
| Alternative Antibody Names | Anti-Ferm - Arhgef And Pleckstrin Domain-Containing Protein 1 antibodyAnti-Chondrocyte-Derived Ezrin-Like Protein antibodyAnti-Ferm - Rhogef And Pleckstrin Domain-Containing Protein 1 antibodyAnti-Pleckstrin Homology Domain-Containing Family C Member 2 antibodyAnti-Ph Domain-Containing Family C Member 2 antibodyAnti-FARP1 antibodyAnti-CDEP antibodyAnti-PLEKHC2 antibody |
Information sourced from Uniprot.org
