| Host: |
Goat |
| Applications: |
Pep-ELISA/IHC |
| Reactivity: |
Human/Mouse/Rat/Dog |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Goat polyclonal antibody anti-FAAH (C-Term) is suitable for use in ELISA and Immunohistochemistry research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Purification: |
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Concentration: |
0.5 mg/mL |
| Dilution Range: |
Peptide ELISA: antibody detection limit dilution 1:64000.IHC: In paraffin embedded Human Cortex shows cytoplasm staining in neuronal cell bodies. Paraffin embedded Human Testis. Recommended concentration: 3.75µg/ml. |
| Storage Instruction: |
Store at-20°C on receipt and minimise freeze-thaw cycles. |
| Gene Symbol: |
FAAH |
| Gene ID: |
2166 |
| Uniprot ID: |
FAAH1_HUMAN |
| Immunogen Region: |
C-Term |
| Accession Number: |
NP_001432.2 |
| Immunogen Sequence: |
REVERLMTPEKQ |
| Function | Catalyzes the hydrolysis of endogenous amidated lipids like the sleep-inducing lipid oleamide ((9Z)-octadecenamide), the endocannabinoid anandamide (N-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-ethanolamine), as well as other fatty amides, to their corresponding fatty acids, thereby regulating the signaling functions of these molecules. Hydrolyzes polyunsaturated substrate anandamide preferentially as compared to monounsaturated substrates. It can also catalyze the hydrolysis of the endocannabinoid 2-arachidonoylglycerol (2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-glycerol). FAAH cooperates with PM20D1 in the hydrolysis of amino acid-conjugated fatty acids such as N-fatty acyl glycine and N-fatty acyl-L-serine, thereby acting as a physiological regulator of specific subsets of intracellular, but not of extracellular, N-fatty acyl amino acids. |
| Protein Name | Fatty-Acid Amide Hydrolase 1Anandamide Amidohydrolase 1Fatty Acid Ester HydrolaseOleamide Hydrolase 1 |
| Database Links | Reactome: R-HSA-2142753 |
| Cellular Localisation | Endomembrane SystemSingle-Pass Membrane ProteinCytoplasmCytoskeletonSeems To Be Attached To Intracellular Membranes And A Portion Of The Cytoskeletal Network |
| Alternative Antibody Names | Anti-Fatty-Acid Amide Hydrolase 1 antibodyAnti-Anandamide Amidohydrolase 1 antibodyAnti-Fatty Acid Ester Hydrolase antibodyAnti-Oleamide Hydrolase 1 antibodyAnti-FAAH antibodyAnti-FAAH1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
