• Western blot analysis of lysates from A431 cells, primary antibody was diluted at 1:1000, 4°C over night

Anti-EXTL2 antibody (141-191 aa) (STJ194954)

SKU:
STJ194954

Current Stock:
Host: Rabbit
Applications: WB
Reactivity: Human/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Exostosin-like 2 (141-191 aa) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: EXTL2
Gene ID: 2135
Uniprot ID: EXTL2_HUMAN
Immunogen Region: 141-191 aa
Specificity: This antibody detects endogenous levels of EXTL2 at Human/Mouse
Immunogen: Synthesized peptide derived from the human EXTL2 at the amino acid range 141-191
Post Translational Modifications The soluble form derives from the membrane form by proteolytic processing.
Function Glycosyltransferase required for the biosynthesis of heparan-sulfate and responsible for the alternating addition of beta-1-4-linked glucuronic acid (GlcA) and alpha-1-4-linked N-acetylglucosamine (GlcNAc) units to nascent heparan sulfate chains.
Protein Name Exostosin-Like 2
Alpha-1 -4-N-Acetylhexosaminyltransferase Extl2
Alpha-Galnact Extl2
Ext-Related Protein 2
Glucuronyl-Galactosyl-Proteoglycan 4-Alpha-N-Acetylglucosaminyltransferase Cleaved Into - Processed Exostosin-Like 2
Database Links Reactome: R-HSA-381038
Cellular Localisation Endoplasmic Reticulum Membrane
Single-Pass Type Ii Membrane Protein
Processed Exostosin-Like 2: Secreted
A Soluble Form Is Found In The Serum
Alternative Antibody Names Anti-Exostosin-Like 2 antibody
Anti-Alpha-1 -4-N-Acetylhexosaminyltransferase Extl2 antibody
Anti-Alpha-Galnact Extl2 antibody
Anti-Ext-Related Protein 2 antibody
Anti-Glucuronyl-Galactosyl-Proteoglycan 4-Alpha-N-Acetylglucosaminyltransferase Cleaved Into - Processed Exostosin-Like 2 antibody
Anti-EXTL2 antibody
Anti-EXTR2 antibody

Information sourced from Uniprot.org

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