• Western blot analysis of extracts of various cell lines, using EXOSC1 antibody (STJ112340) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit.Exposure time: 90s.

Anti-EXOSC1 antibody (STJ112340)

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STJ112340
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Host: Rabbit
Applications: WB
Reactivity: Human
Short Description: Rabbit polyclonal primary antibody against EXOSC1.
Note: FOR RESEARCH USE ONLY (RUO).
Clonality: Polyclonal
Conjugation: Unconjugated
Formulation: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Purification: Affinity purification
Storage Instruction: Store at-20°C. Avoid freeze/thaw cycles.
Isotype: IgG
Dilution Range: WB: 1:500-1:2000
Uniprot ID: EXOS1_HUMAN
Gene ID: 51013
Gene Symbol: EXOSC1
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-195 of human EXOSC1 (NP_057130.1).
Background This gene encodes a core component of the exosome. The mammalian exosome is required for rapid degradation of AU rich element-containing RNAs but not for poly (A) shortening. The association of this protein with the exosome is mediated by protein-protein interactions with ribosomal RNA-processing protein 42 and ribosomal RNA-processing protein 46. Alternative splicing of this gene results in multiple transcript variants.
Database Links Reactome: R-HSA-380994
Cellular Localisation Nucleus
Nucleolus
Cytoplasm
Protein Name Exosome Complex Component Csl4
Exosome Component 1
Alternative Names Anti-Exosome Complex Component Csl4 antibody
Anti-Exosome Component 1 antibody
Anti-EXOSC1 antibody
Anti-CSL4 antibody
Anti-CGI-108 antibody

Information sourced from uniprot.org

6 months standard