Background | This gene encodes a core component of the exosome. The mammalian exosome is required for rapid degradation of AU rich element-containing RNAs but not for poly (A) shortening. The association of this protein with the exosome is mediated by protein-protein interactions with ribosomal RNA-processing protein 42 and ribosomal RNA-processing protein 46. Alternative splicing of this gene results in multiple transcript variants. |
Database Links | Reactome: R-HSA-380994 |
Cellular Localisation | NucleusNucleolusCytoplasm |
Protein Name | Exosome Complex Component Csl4Exosome Component 1 |
Alternative Names | Anti-Exosome Complex Component Csl4 antibodyAnti-Exosome Component 1 antibodyAnti-EXOSC1 antibodyAnti-CSL4 antibodyAnti-CGI-108 antibody |
Information sourced from uniprot.org