Host: | Goat |
Applications: | Pep-ELISA/IF/FC |
Reactivity: | Human/Mouse/Rat/Dog/Cow |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description : | Goat polyclonal antibody anti-ETV1 (Internal) is suitable for use in ELISA, Immunofluorescence and Flow Cytometry research applications. |
Clonality : | Polyclonal |
Conjugation: | Unconjugated |
Isotype: | IgG |
Formulation: | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
Purification: | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
Concentration: | 0.5 mg/mL |
Dilution Range: | Peptide ELISA: antibody detection limit dilution 1:8000.IF: Strong expression of the protein seen in the nuclei of A549 cells. Recommended concentration: 10µg/ml. FC:Flow cytometric analysis of A549 cells. Recommended concentration: 10ug/ml. |
Storage Instruction: | Store at-20°C on receipt and minimise freeze-thaw cycles. |
Gene Symbol: | ETV1 |
Gene ID: | 2115 |
Uniprot ID: | ETV1_HUMAN |
Immunogen Region: | Internal |
Accession Number: | NP_004947.2; NP_001156619.1; NP_001156620.1; NP_001156621.1; NP_001156622.1; NP_001156623.1; NP_001156624.1 |
Specificity: | This antidbody is expected to recognise all reported isoforms. Variants (NP_001156620.1; NP_001156621.1) encode the same isoform. |
Immunogen Sequence: | PLKIKKEPHSPCSE |
Post Translational Modifications | Sumoylated. Phosphorylated at Ser-191 and Ser-216 by RPS6KA1 and RPS6KA5.phosphorylation activates transcriptional activity. |
Function | Transcriptional activator that binds to DNA sequences containing the consensus pentanucleotide 5'-CGGAAT-3'. Required for olfactory dopaminergic neuron differentiation.may directly activate expression of tyrosine hydroxylase (TH). |
Protein Name | Ets Translocation Variant 1Ets-Related Protein 81 |
Cellular Localisation | Nucleus |
Alternative Antibody Names | Anti-Ets Translocation Variant 1 antibodyAnti-Ets-Related Protein 81 antibodyAnti-ETV1 antibodyAnti-ER81 antibody |
Information sourced from Uniprot.org