Anti-ETFA antibody (1-333) (STJ29983)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal ETFA (1-333) antibody for use in WB, IHC-P, IP and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC-P/IP/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000IHC-P:1:50-1:200IP:0.5 Mu g-4 Mu g antibody for 200 Mu g-400 Mu g extracts of whole cellsELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | ETFA |
| Gene ID | 2108 |
| Uniprot ID | ETFA_HUMAN |
| Immunogen Region | 1-333 |
| Immunogen Sequence | MFRAAAPGQLRRAASLLRFQ STLVIAEHANDSLAPITLNT ITAATRLGGEVSCLVAGTKC DKVAQDLCKVAGIAKVLVAQ HDVYKGLLPEELTPLILATQ KQFNYTHICAGASAFGKNLL PRVAAKLEVAPISDIIAIKS PDTFVRTIYAGNALCTVKCD EKVKVFSVRGTSFDAAATSG GSASSEKASSTSPVEISEWL DQKLTKSDRPELTGAKVVVS GGRGLKSGENFKLLYDLAD |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 1-333 of human ETFA (NP_000117.1). |
Additional Info
| Post Translational Modifications | The N-terminus is blocked. |
| Function | Heterodimeric electron transfer flavoprotein that accepts electrons from several mitochondrial dehydrogenases, including acyl-CoA dehydrogenases, glutaryl-CoA and sarcosine dehydrogenase. It transfers the electrons to the main mitochondrial respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase). Required for normal mitochondrial fatty acid oxidation and normal amino acid metabolism. |
| Protein Name | Electron Transfer Flavoprotein Subunit Alpha - MitochondrialAlpha-Etf |
| Database Links | Reactome: R-HSA-611105 |
| Cellular Localisation | Mitochondrion Matrix |
| Alternative Antibody Names | Anti-Electron Transfer Flavoprotein Subunit Alpha - Mitochondrial antibodyAnti-Alpha-Etf antibodyAnti-ETFA antibody |
Information sourced from Uniprot.org