| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | ESAM |
| Gene ID: | 90952 |
| Uniprot ID: | ESAM_HUMAN |
| Immunogen Region: | 30-248 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 30-248 of human ESAM (NP_620411.2). |
| Immunogen Sequence: | QLQLHLPANRLQAVEGGEVV LPAWYTLHGEVSSSQPWEVP FVMWFFKQKEKEDQVLSYIN GVTTSKPGVSLVYSMPSRNL SLRLEGLQEKDSGPYSCSVN VQDKQGKSRGHSIKTLELNV LVPPAPPSCRLQGVPHVGAN VTLSCQSPRSKPAVQYQWDR QLPSFQTFFAPALDVIRGSL SLTNLSSSMAGVYVCKAHNE VGTAQCNVTLEVSTGPGAA |
| Tissue Specificity | Highly expressed in endothelial cells. |
| Function | Can mediate aggregation most likely through a homophilic molecular interaction. |
| Protein Name | Endothelial Cell-Selective Adhesion Molecule |
| Database Links | Reactome: R-HSA-202733 |
| Cellular Localisation | Cell JunctionAdherens JunctionTight JunctionCell MembraneSingle-Pass Type I Membrane Protein |
| Alternative Antibody Names | Anti-Endothelial Cell-Selective Adhesion Molecule antibodyAnti-ESAM antibodyAnti-UNQ220 antibodyAnti-PRO246 antibody |
Information sourced from Uniprot.org