Anti-ESAM antibody (30-248) (STJ114102)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal ESAM (30-248) antibody for use in WB and ELISA in human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | ESAM |
| Gene ID | 90952 |
| Uniprot ID | ESAM_HUMAN |
| Immunogen Region | 30-248 |
| Immunogen Sequence | QLQLHLPANRLQAVEGGEVV LPAWYTLHGEVSSSQPWEVP FVMWFFKQKEKEDQVLSYIN GVTTSKPGVSLVYSMPSRNL SLRLEGLQEKDSGPYSCSVN VQDKQGKSRGHSIKTLELNV LVPPAPPSCRLQGVPHVGAN VTLSCQSPRSKPAVQYQWDR QLPSFQTFFAPALDVIRGSL SLTNLSSSMAGVYVCKAHNE VGTAQCNVTLEVSTGPGAA |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 30-248 of human ESAM (NP_620411.2). |
Additional Info
| Tissue Specificity | Highly expressed in endothelial cells. |
| Function | Can mediate aggregation most likely through a homophilic molecular interaction. |
| Protein Name | Endothelial Cell-Selective Adhesion Molecule |
| Database Links | Reactome: R-HSA-202733 |
| Cellular Localisation | Cell JunctionAdherens JunctionTight JunctionCell MembraneSingle-Pass Type I Membrane Protein |
| Alternative Antibody Names | Anti-Endothelial Cell-Selective Adhesion Molecule antibodyAnti-ESAM antibodyAnti-UNQ220 antibodyAnti-PRO246 antibody |
Information sourced from Uniprot.org