| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | ERCC6L2 |
| Gene ID: | 375748 |
| Uniprot ID: | ER6L2_HUMAN |
| Immunogen Region: | 1262-1561 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1262-1561 of human ERCC6L2 (NP_064592.2). |
| Immunogen Sequence: | TSEERQKMLRDFYASQYPEV KEFFVDSVSQFNNSSFEKGE QRTRKKSDKRESLIKPRLSD SETLSFKDSTNKISQVCSLK TYKRKSVKFQNHISYREEVF FNDAETKKSPVSSTQEIDSG KNSQASEDTVTSRSLNSESE TRERRLENTMKDQQDLTRTG ISRKEPLLKLENKKIENPVL ENTSVISLLGDTSILDDLFK SHGNSPTQLPKKVLSGPMEK AKQRPKDFWDILNEQNDES |
| Tissue Specificity | Expressed in bone marrow (at protein level). |
| Post Translational Modifications | Phosphorylated by NEK6. |
| Function | May be involved in early DNA damage response. |
| Protein Name | Dna Excision Repair Protein Ercc-6-Like 2Dna Repair And Recombination Protein Rad26-Like |
| Cellular Localisation | NucleusCytoplasmCytoskeletonMicrotubule Organizing CenterCentrosomeMitochondrionColocalizes With Nek6 In The CentrosomeIn Response To Dna DamageTranslocates From The Cytosol To Mitochondria And Nucleus In A Reactive Oxygen Species (Ros)-Dependent Manner |
| Alternative Antibody Names | Anti-Dna Excision Repair Protein Ercc-6-Like 2 antibodyAnti-Dna Repair And Recombination Protein Rad26-Like antibodyAnti-ERCC6L2 antibodyAnti-C9orf102 antibodyAnti-RAD26L antibody |
Information sourced from Uniprot.org
