• Western blot analysis of various lysates using ERCC6L2 Rabbit polyclonal antibody (STJ115110) at 1:3000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit. Exposure time: 60s.

Anti-ERCC6L2 antibody (1262-1561) (STJ115110)

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STJ115110

£112.50 - £522.50
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Host: Rabbit
Applications: WB
Reactivity: Human/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-ERCC6L2 (1262-1561) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: ERCC6L2
Gene ID: 375748
Uniprot ID: ER6L2_HUMAN
Immunogen Region: 1262-1561
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1262-1561 of human ERCC6L2 (NP_064592.2).
Immunogen Sequence: TSEERQKMLRDFYASQYPEV KEFFVDSVSQFNNSSFEKGE QRTRKKSDKRESLIKPRLSD SETLSFKDSTNKISQVCSLK TYKRKSVKFQNHISYREEVF FNDAETKKSPVSSTQEIDSG KNSQASEDTVTSRSLNSESE TRERRLENTMKDQQDLTRTG ISRKEPLLKLENKKIENPVL ENTSVISLLGDTSILDDLFK SHGNSPTQLPKKVLSGPMEK AKQRPKDFWDILNEQNDES
Tissue Specificity Expressed in bone marrow (at protein level).
Post Translational Modifications Phosphorylated by NEK6.
Function May be involved in early DNA damage response.
Protein Name Dna Excision Repair Protein Ercc-6-Like 2
Dna Repair And Recombination Protein Rad26-Like
Cellular Localisation Nucleus
Cytoplasm
Cytoskeleton
Microtubule Organizing Center
Centrosome
Mitochondrion
Colocalizes With Nek6 In The Centrosome
In Response To Dna Damage
Translocates From The Cytosol To Mitochondria And Nucleus In A Reactive Oxygen Species (Ros)-Dependent Manner
Alternative Antibody Names Anti-Dna Excision Repair Protein Ercc-6-Like 2 antibody
Anti-Dna Repair And Recombination Protein Rad26-Like antibody
Anti-ERCC6L2 antibody
Anti-C9orf102 antibody
Anti-RAD26L antibody

Information sourced from Uniprot.org

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