• Western blot analysis of lysates from HepG2, Jurkat, and HUVEC cells, using ARTS-1 Antibody. The lane on the right is blocked with the synthesized peptide.
  • Western blot analysis of the lysates from HepG2 cells using ARTS-1 antibody.
  • Western blot analysis of various cells using ERAP1 Polyclonal Antibody diluted at 1：500

Anti-ERAP1 antibody (441-490 aa) (STJ92971)

SKU:
STJ92971

£46.00 - £226.00
Current Stock:
Host: Rabbit
Applications: WB/IHC/IF/ELISA
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Endoplasmic reticulum aminopeptidase 1 (441-490 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-1:2000
IHC 1:100-1:300
IF 1:200-1:1000
ELISA 1:20000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: ERAP1
Gene ID: 51752
Uniprot ID: ERAP1_HUMAN
Immunogen Region: 441-490 aa
Specificity: ERAP1 Polyclonal Antibody detects endogenous levels of ERAP1 protein.
Immunogen: The antiserum was produced against synthesized peptide derived from the human ARTS-1 at the amino acid range 441-490
Post Translational Modifications N-glycosylated.
Function Aminopeptidase that plays a central role in peptide trimming, a step required for the generation of most HLA class I-binding peptides. Peptide trimming is essential to customize longer precursor peptides to fit them to the correct length required for presentation on MHC class I molecules. Strongly prefers substrates 9-16 residues long. Rapidly degrades 13-mer to a 9-mer and then stops. Preferentially hydrolyzes the residue Leu and peptides with a hydrophobic C-terminus, while it has weak activity toward peptides with charged C-terminus. May play a role in the inactivation of peptide hormones. May be involved in the regulation of blood pressure through the inactivation of angiotensin II and/or the generation of bradykinin in the kidney.
Protein Name Endoplasmic Reticulum Aminopeptidase 1
Arts-1
Adipocyte-Derived Leucine Aminopeptidase
A-Lap
Aminopeptidase Pils
Puromycin-Insensitive Leucyl-Specific Aminopeptidase
Pils-Ap
Type 1 Tumor Necrosis Factor Receptor Shedding Aminopeptidase Regulator
Database Links Reactome: R-HSA-983170
Cellular Localisation Endoplasmic Reticulum Membrane
Single-Pass Type Ii Membrane Protein
Alternative Antibody Names Anti-Endoplasmic Reticulum Aminopeptidase 1 antibody
Anti-Arts-1 antibody
Anti-Adipocyte-Derived Leucine Aminopeptidase antibody
Anti-A-Lap antibody
Anti-Aminopeptidase Pils antibody
Anti-Puromycin-Insensitive Leucyl-Specific Aminopeptidase antibody
Anti-Pils-Ap antibody
Anti-Type 1 Tumor Necrosis Factor Receptor Shedding Aminopeptidase Regulator antibody
Anti-ERAP1 antibody
Anti-APPILS antibody
Anti-ARTS1 antibody
Anti-KIAA0525 antibody
Anti-UNQ584 antibody
Anti-PRO1154 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance