| Host: |
Rabbit |
| Applications: |
WB/ELISA |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-Epsin-1 (140-220 aa) is suitable for use in Western Blot and ELISA research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:500-1:2000ELISA 1:40000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
EPN1 |
| Gene ID: |
29924 |
| Uniprot ID: |
EPN1_HUMAN |
| Immunogen Region: |
140-220 aa |
| Specificity: |
Epsin 1 Polyclonal Antibody detects endogenous levels of Epsin 1 protein. |
| Immunogen: |
Synthesized peptide derived from Epsin 1 at the amino acid range 140-220 |
| Function | Binds to membranes enriched in phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2). Modifies membrane curvature and facilitates the formation of clathrin-coated invaginations. Regulates receptor-mediated endocytosis. |
| Protein Name | Epsin-1Eh Domain-Binding Mitotic PhosphoproteinEps-15-Interacting Protein 1 |
| Database Links | Reactome: R-HSA-182971Reactome: R-HSA-8856825Reactome: R-HSA-8856828 |
| Cellular Localisation | CytoplasmCell MembranePeripheral Membrane ProteinNucleusMembraneClathrin-Coated PitAssociated With The Cytoplasmic Membrane At Sites Where Clathrin-Coated Pits Are FormingColocalizes With Clathrin And Ap-2 In A Punctate Pattern On The Plasma MembraneDetected In Presynaptic Nerve Terminals And In Golgi StacksMay Shuttle To The Nucleus When Associated With Zbtb16/Znf145 |
| Alternative Antibody Names | Anti-Epsin-1 antibodyAnti-Eh Domain-Binding Mitotic Phosphoprotein antibodyAnti-Eps-15-Interacting Protein 1 antibodyAnti-EPN1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
