Anti-EPHX1 antibody (20-320) (STJ23551)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal EPHX1 (20-320) antibody for use in WB and ELISA in human and mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | EPHX1 |
| Gene ID | 2052 |
| Uniprot ID | HYEP_HUMAN |
| Immunogen Region | 20-320 |
| Immunogen Sequence | SRDKEETLPLEDGWWGPGTR SAAREDDSIRPFKVETSDEE IHDLHQRIDKFRFTPPLEDS CFHYGFNSNYLKKVISYWRN EFDWKKQVEILNRYPHFKTK IEGLDIHFIHVKPPQLPAGH TPKPLLMVHGWPGSFYEFYK IIPLLTDPKNHGLSDEHVFE VICPSIPGYGFSEASSKKGF NSVATARIFYKLMLRLGFQE FYIQGGDWGSLICTNMAQLV PSHVKGLHLNMALVLSNFS |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 20-320 of human EPHX1 (NP_000111.1). |
Additional Info
| Tissue Specificity | Found in liver. |
| Function | Biotransformation enzyme that catalyzes the hydrolysis of arene and aliphatic epoxides to less reactive and more water soluble dihydrodiols by the trans addition of water. Plays a role in the metabolism of endogenous lipids such as epoxide-containing fatty acids. Metabolizes the abundant endocannabinoid 2-arachidonoylglycerol (2-AG) to free arachidonic acid (AA) and glycerol. Binds 20(S)-hydroxycholesterol (20(S)-OHC). |
| Protein Name | Epoxide Hydrolase 1Epoxide HydrataseMicrosomal Epoxide HydrolaseMeh |
| Database Links | Reactome: R-HSA-211945 |
| Cellular Localisation | Microsome MembraneSingle-Pass Type Iii Membrane ProteinEndoplasmic Reticulum Membrane |
| Alternative Antibody Names | Anti-Epoxide Hydrolase 1 antibodyAnti-Epoxide Hydratase antibodyAnti-Microsomal Epoxide Hydrolase antibodyAnti-Meh antibodyAnti-EPHX1 antibodyAnti-EPHX antibodyAnti-EPOX antibody |
Information sourced from Uniprot.org