| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-Endosome-associated-trafficking regulator 1 is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:500-2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
ENTR1 |
| Gene ID: |
10807 |
| Uniprot ID: |
ENTR1_HUMAN |
| Specificity: |
This antibody detects endogenous levels of SDCCAG3 at Human, Mouse |
| Immunogen: |
Synthesized peptide derived from human SDCCAG3 |
| Post Translational Modifications | Phosphorylated. |
| Function | Endosome-associated protein that plays a role in membrane receptor sorting, cytokinesis and ciliogenesis. Involved in the endosome-to-plasma membrane trafficking and recycling of SNX27-retromer-dependent cargo proteins, such as GLUT1. Involved in the regulation of cytokinesis.the function may involve PTPN13 and GIT1. Plays a role in the formation of cilia. Involved in cargo protein localization, such as PKD2, at primary cilia. Involved in the presentation of the tumor necrosis factor (TNF) receptor TNFRSF1A on the cell surface, and hence in the modulation of the TNF-induced apoptosis. |
| Protein Name | Endosome-Associated-Trafficking Regulator 1Antigen Ny-Co-3Serologically Defined Colon Cancer Antigen 3 |
| Cellular Localisation | CytoplasmEarly EndosomeEndosomeRecycling EndosomeMidbodyCytoskeletonMicrotubule Organizing CenterCentrosomeCilium Basal BodyColocalizes In A Washc2-Dependent Manner With The Retromer Csc Complex At EndosomesDuring Cytokinesis Colocalized With Ptpn13 At The MidbodyColocalizes With Ift88 And Gamma-Tubulin At The Basal Body Of Primary CiliaColocalizes With Ift88 And Pericentrin At The Centrosome |
| Alternative Antibody Names | Anti-Endosome-Associated-Trafficking Regulator 1 antibodyAnti-Antigen Ny-Co-3 antibodyAnti-Serologically Defined Colon Cancer Antigen 3 antibodyAnti-ENTR1 antibodyAnti-SDCCAG3 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
