| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-ENO2 (1-127) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:100-1:500 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
ENO2 |
| Gene ID: |
2026 |
| Uniprot ID: |
ENOG_HUMAN |
| Immunogen Region: |
1-127 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-127 of human ENO2 (NP_001966.1). |
| Immunogen Sequence: |
MSIEKIWAREILDSRGNPTV EVDLYTAKGLFRAAVPSGAS TGIYEALELRDGDKQRYLGK GVLKAVDHINSTIAPALISS GLSVVEQEKLDNLMLELDGT ENKSKFGANAILGVSLAVCK AGAAERE |
| Tissue Specificity | The alpha/alpha homodimer is expressed in embryo and in most adult tissues. The alpha/beta heterodimer and the beta/beta homodimer are found in striated muscle, and the alpha/gamma heterodimer and the gamma/gamma homodimer in neurons. |
| Function | Has neurotrophic and neuroprotective properties on a broad spectrum of central nervous system (CNS) neurons. Binds, in a calcium-dependent manner, to cultured neocortical neurons and promotes cell survival. |
| Protein Name | Gamma-Enolase2-Phospho-D-Glycerate Hydro-LyaseEnolase 2Neural EnolaseNeuron-Specific EnolaseNse |
| Database Links | Reactome: R-HSA-70171Reactome: R-HSA-70263 |
| Cellular Localisation | CytoplasmCell MembraneCan Translocate To The Plasma Membrane In Either The Homodimeric (Alpha/Alpha) Or Heterodimeric (Alpha/Gamma) Form |
| Alternative Antibody Names | Anti-Gamma-Enolase antibodyAnti-2-Phospho-D-Glycerate Hydro-Lyase antibodyAnti-Enolase 2 antibodyAnti-Neural Enolase antibodyAnti-Neuron-Specific Enolase antibodyAnti-Nse antibodyAnti-ENO2 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
