Anti-ENO2 antibody (1-127) (STJ23539)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal ENO2 (1-127) antibody for use in WB and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:1000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | ENO2 |
| Gene ID | 2026 |
| Uniprot ID | ENOG_HUMAN |
| Immunogen Region | 1-127 |
| Immunogen Sequence | MSIEKIWAREILDSRGNPTV EVDLYTAKGLFRAAVPSGAS TGIYEALELRDGDKQRYLGK GVLKAVDHINSTIAPALISS GLSVVEQEKLDNLMLELDGT ENKSKFGANAILGVSLAVCK AGAAERE |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 1-127 of human ENO2 (NP_001966.1). |
Additional Info
| Tissue Specificity | The alpha/alpha homodimer is expressed in embryo and in most adult tissues. The alpha/beta heterodimer and the beta/beta homodimer are found in striated muscle, and the alpha/gamma heterodimer and the gamma/gamma homodimer in neurons. |
| Function | Has neurotrophic and neuroprotective properties on a broad spectrum of central nervous system (CNS) neurons. Binds, in a calcium-dependent manner, to cultured neocortical neurons and promotes cell survival. |
| Protein Name | Gamma-Enolase2-Phospho-D-Glycerate Hydro-LyaseEnolase 2Neural EnolaseNeuron-Specific EnolaseNse |
| Database Links | Reactome: R-HSA-70171Reactome: R-HSA-70263 |
| Cellular Localisation | CytoplasmCell MembraneCan Translocate To The Plasma Membrane In Either The Homodimeric (Alpha/Alpha) Or Heterodimeric (Alpha/Gamma) Form |
| Alternative Antibody Names | Anti-Gamma-Enolase antibodyAnti-2-Phospho-D-Glycerate Hydro-Lyase antibodyAnti-Enolase 2 antibodyAnti-Neural Enolase antibodyAnti-Neuron-Specific Enolase antibodyAnti-Nse antibodyAnti-ENO2 antibody |
Information sourced from Uniprot.org