• STJ72868 (0. 3µg/ml) staining of Human Frontal Cortex lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Anti-Endophilin-A1/SH3GL2 antibody (Internal) (STJ72868)

SKU:
STJ72868-100

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Host: Goat
Applications: Pep-ELISA/WB/IHC
Reactivity: Human/Pig
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Goat polyclonal antibody anti-Endophilin-A1/SH3GL2 (Internal) is suitable for use in ELISA, Western Blot and Immunohistochemistry research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA
Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Concentration: 0.5 mg/mL
Dilution Range: WB-0.3-1µg/ml
IHC-Recommended concentration, 5-10µg/ml
ELISA-antibody detection limit dilution 1:64000.
Storage Instruction: Store at-20°C on receipt and minimise freeze-thaw cycles.
Gene Symbol: SH3GL2
Gene ID: 6456
Uniprot ID: SH3G2_HUMAN
Immunogen Region: Internal
Accession Number: NP_003017.1
Immunogen Sequence: SLEFPTGDSTQPN
Function Implicated in synaptic vesicle endocytosis. May recruit other proteins to membranes with high curvature. Required for BDNF-dependent dendrite outgrowth. Cooperates with SH3GL2 to mediate BDNF-NTRK2 early endocytic trafficking and signaling from early endosomes.
Protein Name Endophilin-A1
Een-B1
Endophilin-1
Sh3 Domain Protein 2a
Sh3 Domain-Containing Grb2-Like Protein 2
Database Links Reactome: R-HSA-177504
Reactome: R-HSA-182971
Reactome: R-HSA-2132295
Reactome: R-HSA-432720
Reactome: R-HSA-432722
Reactome: R-HSA-437239
Reactome: R-HSA-6807004
Reactome: R-HSA-8856825
Reactome: R-HSA-8856828
Reactome: R-HSA-8875360
Cellular Localisation Cytoplasm
Membrane
Peripheral Membrane Protein
Early Endosome
Presynapse
Alternative Antibody Names Anti-Endophilin-A1 antibody
Anti-Een-B1 antibody
Anti-Endophilin-1 antibody
Anti-Sh3 Domain Protein 2a antibody
Anti-Sh3 Domain-Containing Grb2-Like Protein 2 antibody
Anti-SH3GL2 antibody
Anti-CNSA2 antibody
Anti-SH3D2A antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance