| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | ENDOD1 |
| Gene ID: | 23052 |
| Uniprot ID: | ENDD1_HUMAN |
| Immunogen Region: | 22-330 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 22-330 of human ENDOD1 (NP_055851.1). |
| Immunogen Sequence: | RLVGEEEAGFGECDKFFYAG TPPAGLAADSHVKICQRAEG AERFATLYSTRDRIPVYSAF RAPRPAPGGAEQRWLVEPQI DDPNSNLEEAINEAEAITSV NSLGSKQALNTDYLDSDYQR GQLYPFSLSSDVQVATFTLT NSAPMTQSFQERWYVNLHSL MDRALTPQCGSGEDLYILTG TVPSDYRVKDKVAVPEFVWL AACCAVPGGGWAMGFVKHTR DSDIIEDVMVKDLQKLLPF |
| Function | May act as a DNase and a RNase. Plays a role in the modulation of innate immune signaling through the cGAS-STING pathway by interacting with RNF26. |
| Protein Name | Endonuclease Domain-Containing 1 Protein |
| Database Links | Reactome: R-HSA-114608 |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-Endonuclease Domain-Containing 1 Protein antibodyAnti-ENDOD1 antibodyAnti-KIAA0830 antibody |
Information sourced from Uniprot.org