Tissue Specificity | Widely expressed. Highly expressed in heart, placenta, liver, skeletal muscle, kidney, pancreas, testis and ovary. Weakly expressed in brain, lung, spleen, thymus, prostate, small intestine, colon and leukocytes. |
Function | Zinc phosphodiesterase, which displays mitochondrial tRNA 3'-processing endonuclease activity. Involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA. Associates with mitochondrial DNA complexes at the nucleoids to initiate RNA processing and ribosome assembly. |
Protein Name | Zinc Phosphodiesterase Elac Protein 2Elac Homolog Protein 2Heredity Prostate Cancer Protein 2Ribonuclease Z 2Rnase Z 2Trna 3 Endonuclease 2Trnase Z 2 |
Database Links | Reactome: R-HSA-6784531Reactome: R-HSA-6785470Reactome: R-HSA-8868766Reactome: R-HSA-9708296 |
Cellular Localisation | MitochondrionMitochondrion MatrixMitochondrion NucleoidNucleusMainly Mitochondrial |
Alternative Antibody Names | Anti-Zinc Phosphodiesterase Elac Protein 2 antibodyAnti-Elac Homolog Protein 2 antibodyAnti-Heredity Prostate Cancer Protein 2 antibodyAnti-Ribonuclease Z 2 antibodyAnti-Rnase Z 2 antibodyAnti-Trna 3 Endonuclease 2 antibodyAnti-Trnase Z 2 antibodyAnti-ELAC2 antibodyAnti-HPC2 antibody |
Information sourced from Uniprot.org