Host: |
Rabbit |
Applications: |
WB/IHC/IF/ELISA |
Reactivity: |
Human/Rat/Mouse |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit polyclonal antibody anti-EP300-interacting inhibitor of differentiation 1 (71-120 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Concentration: |
1 mg/mL |
Dilution Range: |
WB 1:500-1:2000IHC 1:100-1:300IF 1:200-1:1000ELISA 1:10000 |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
EID1 |
Gene ID: |
23741 |
Uniprot ID: |
EID1_HUMAN |
Immunogen Region: |
71-120 aa |
Specificity: |
EID-1 Polyclonal Antibody detects endogenous levels of EID-1 protein. |
Immunogen: |
The antiserum was produced against synthesized peptide derived from the human EID1 at the amino acid range 71-120 |
Post Translational Modifications | Ubiquitinated in U2OS osteosarcoma cells and is rapidly degraded by proteasome as cells exit the cell cycle exit. |
Function | Interacts with RB1 and EP300 and acts as a repressor of MYOD1 transactivation. Inhibits EP300 and CBP histone acetyltransferase activity. May be involved in coupling cell cycle exit to the transcriptional activation of genes required for cellular differentiation. May act as a candidate coinhibitory factor for NR0B2 that can be directly linked to transcription inhibitory mechanisms. |
Protein Name | Ep300-Interacting Inhibitor Of Differentiation 121 Kda Prb-Associated ProteinCrebbp/Ep300 Inhibitory Protein 1E1a-Like Inhibitor Of Differentiation 1Eid-1 |
Cellular Localisation | NucleusCytoplasmMay Shuttle Between Nucleus And Cytoplasm |
Alternative Antibody Names | Anti-Ep300-Interacting Inhibitor Of Differentiation 1 antibodyAnti-21 Kda Prb-Associated Protein antibodyAnti-Crebbp/Ep300 Inhibitory Protein 1 antibodyAnti-E1a-Like Inhibitor Of Differentiation 1 antibodyAnti-Eid-1 antibodyAnti-EID1 antibodyAnti-C15orf3 antibodyAnti-CRI1 antibodyAnti-RBP21 antibodyAnti-PNAS-22 antibodyAnti-PTD014 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance