| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-EFS (60-190) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
EFS |
| Gene ID: |
10278 |
| Uniprot ID: |
EFS_HUMAN |
| Immunogen Region: |
60-190 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 60-190 of human EFS (NP_115835.1). |
| Immunogen Sequence: |
TALRVPSSGPYDCPASFSHP LTRVAPQPPGEDDAPYDVPL TPKPPAELEPDLEWEGGREP GPPIYAAPSNLKRASALLNL YEAPEELLADGEGGGTDEGI YDVPLLGPEAPPSPEPPGAL ASHDQDTLAQL |
| Tissue Specificity | The protein has been detected in lung and placenta. |
| Post Translational Modifications | Phosphorylated on multiple tyrosine residues. Phosphorylated on tyrosines by FYN and SRC. |
| Function | Docking protein which plays a central coordinating role for tyrosine-kinase-based signaling related to cell adhesion. May serve as an activator of SRC and a downstream effector. Interacts with the SH3 domain of FYN and with CRK, SRC, and YES. |
| Protein Name | Embryonal Fyn-Associated SubstrateHefsCas Scaffolding Protein Family Member 3 |
| Alternative Antibody Names | Anti-Embryonal Fyn-Associated Substrate antibodyAnti-Hefs antibodyAnti-Cas Scaffolding Protein Family Member 3 antibodyAnti-EFS antibodyAnti-CASS3 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
