| Short Description : | Rabbit polyclonal EFHD2 (1-78) antibody for use in WB and ELISA in mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB/ELISA |
| Host: | Rabbit |
| Reactivity: | Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | Lot specific |
| Purification: | Affinity purification |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | EFHD2 |
| Gene ID: | 79180 |
| Uniprot ID: | EFHD2_HUMAN |
| Immunogen Region: | 1-78 |
| Immunogen Sequence: | MATDELATKLSRRLQMEGEG GGETPEQPGLNGAAAAAAGA PDEAAEALGSADCELSAKLL RRADLNQGIGEPQSPSRR |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-78 of human EFHD2 (NP_077305.2). |
| Tissue Specificity | Found in lymphocytes.preferentially expressed in CD8+ cells. |
| Function | May regulate B-cell receptor (BCR)-induced immature and primary B-cell apoptosis. Plays a role as negative regulator of the canonical NF-kappa-B-activating branch. Controls spontaneous apoptosis through the regulation of BCL2L1 abundance. |
| Protein Name | Ef-Hand Domain-Containing Protein D2Swiprosin-1 |
| Database Links | Reactome: R-HSA-9013405 |
| Cellular Localisation | Membrane RaftIn A Mouse Immature B-Cell Line Wehi-231 |
| Alternative Antibody Names | Anti-Ef-Hand Domain-Containing Protein D2 antibodyAnti-Swiprosin-1 antibodyAnti-EFHD2 antibodyAnti-SWS1 antibody |
Information sourced from Uniprot.org
