Anti-EFEMP1 antibody (111-160 aa) (STJ93073)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenThe antiserum was produced against synthesized peptide derived from the human EFEMP1 at the amino acid range 111-160
General Information
| Short Description | Rabbit polyclonal anti-EGF-containing fibulin-like extracellular matrix protein 1 (111-160 aa) for use in WB, IHC, IF and ELISA in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC/IF/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-1:2000IHC 1:100-1:300ELISA 1:10000IF 1:50-200 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | EFEMP1 |
| Gene ID | 2202 |
| Uniprot ID | FBLN3_HUMAN |
| Immunogen | The antiserum was produced against synthesized peptide derived from the human EFEMP1 at the amino acid range 111-160 |
| Immunogen Region | 111-160 aa |
| Specificity | Fibulin-3 Polyclonal Antibody detects endogenous levels of Fibulin-3 protein. |
Additional Info
| Function | Binds EGFR, the EGF receptor, inducing EGFR autophosphorylation and the activation of downstream signaling pathways. May play a role in cell adhesion and migration. May function as a negative regulator of chondrocyte differentiation. In the olfactory epithelium, it may regulate glial cell migration, differentiation and the ability of glial cells to support neuronal neurite outgrowth. |
| Protein Name | Egf-Containing Fibulin-Like Extracellular Matrix Protein 1Extracellular Protein S1-5Fibrillin-Like ProteinFibulin-3Fibl-3 |
| Database Links | Reactome: R-HSA-2129379 |
| Cellular Localisation | SecretedExtracellular SpaceExtracellular MatrixLocalizes To The Lamina Propria Underneath The Olfactory Epithelium |
| Alternative Antibody Names | Anti-Egf-Containing Fibulin-Like Extracellular Matrix Protein 1 antibodyAnti-Extracellular Protein S1-5 antibodyAnti-Fibrillin-Like Protein antibodyAnti-Fibulin-3 antibodyAnti-Fibl-3 antibodyAnti-EFEMP1 antibodyAnti-FBLN3 antibodyAnti-FBNL antibody |
Information sourced from Uniprot.org