Host: |
Rabbit |
Applications: |
WB |
Reactivity: |
Mouse/Rat |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit polyclonal antibody anti-EDARADD (1-215) is suitable for use in Western Blot research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
Purification: |
Affinity purification |
Dilution Range: |
WB 1:500-1:2000 |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
EDARADD |
Gene ID: |
128178 |
Uniprot ID: |
EDAD_HUMAN |
Immunogen Region: |
1-215 |
Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-215 of human EDARADD (NP_665860.2). |
Immunogen Sequence: |
MGLRTTKQMGRGTKAPGHQE DHMVKEPVEDTDPSTLSFNM SDKYPIQDTELPKAEECDTI TLNCPRNSDMKNQGEENGFP DSTGDPLPEISKDNSCKENC TCSSCLLRAPTISDLLNDQD LLDVIRIKLDPCHPTVKNWR NFASKWGMSYDELCFLEQRP QSPTLEFLLRNSQRTVGQLM ELCRLYHRADVEKVLRRWVD EEWPKRERGDPSRHF |
Tissue Specificity | Detected in adult pancreas, placenta and fetal skin, and at lower levels in lung, thymus, prostate and testis. |
Function | Adapter protein that interacts with EDAR DEATH domain and couples the receptor to EDA signaling pathway during morphogenesis of ectodermal organs. Mediates the activation of NF-kappa-B. |
Protein Name | Ectodysplasin-A Receptor-Associated Adapter ProteinEdar-Associated Death Domain ProteinProtein Crinkled Homolog |
Database Links | Reactome: R-HSA-5669034 |
Cellular Localisation | Cytoplasm |
Alternative Antibody Names | Anti-Ectodysplasin-A Receptor-Associated Adapter Protein antibodyAnti-Edar-Associated Death Domain Protein antibodyAnti-Protein Crinkled Homolog antibodyAnti-EDARADD antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance