| Short Description : | Rabbit polyclonal anti-Tumor necrosis factor receptor superfamily member EDAR (50-130 aa) for use in WB and ELISA in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB/ELISA |
| Host: | Rabbit |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | 1 mg/mL |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range: | WB 1:500-2000ELISA 1:5000-20000 |
| Formulation: | Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | EDAR |
| Gene ID: | 10913 |
| Uniprot ID: | EDAR_HUMAN |
| Immunogen: | Synthesized peptide derived from the human protein at the amino acid range 50-130 |
| Immunogen Region: | 50-130 aa |
| Specificity: | EDAR Polyclonal Antibody detects endogenous levels of protein. |
| Function | Receptor for EDA isoform A1, but not for EDA isoform A2. Mediates the activation of NF-kappa-B and JNK. May promote caspase-independent cell death. |
| Protein Name | Tumor Necrosis Factor Receptor Superfamily Member EdarAnhidrotic Ectodysplasin Receptor 1Downless HomologEda-A1 ReceptorEctodermal Dysplasia ReceptorEctodysplasin-A Receptor |
| Database Links | Reactome: R-HSA-5669034 |
| Cellular Localisation | MembraneSingle-Pass Type I Membrane Protein |
| Alternative Antibody Names | Anti-Tumor Necrosis Factor Receptor Superfamily Member Edar antibodyAnti-Anhidrotic Ectodysplasin Receptor 1 antibodyAnti-Downless Homolog antibodyAnti-Eda-A1 Receptor antibodyAnti-Ectodermal Dysplasia Receptor antibodyAnti-Ectodysplasin-A Receptor antibodyAnti-EDAR antibodyAnti-DL antibody |
Information sourced from Uniprot.org
