| Host: | Rabbit |
| Applications: | WB/IF/ICC/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.05% Proclin300, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:1000-1:5000IF/ICC:1:500-1:1000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | DUSP8 |
| Gene ID: | 1850 |
| Uniprot ID: | DUS8_HUMAN |
| Immunogen Region: | 1-14 |
| Specificity: | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human DUSP8 (NP_004411.2). |
| Immunogen Sequence: | MAGDRLPRKVMDAKKLASLL RGGPGGPLVIDSRSFVEYNS WHVLSSVNICCSKLVKRRLQ QGKVTIAELIQPAARSQVEA TEPQDVVVYDQSTRDASVLA |
| Tissue Specificity | Abundant in brain, heart and skeletal muscle. |
| Function | Has phosphatase activity with synthetic phosphatase substrates and negatively regulates mitogen-activated protein kinase activity, presumably by catalysing their dephosphorylation. Expected to display protein phosphatase activity toward phosphotyrosine, phosphoserine and phosphothreonine residues. |
| Protein Name | Dual Specificity Protein Phosphatase 8Dual Specificity Protein Phosphatase Hvh-5 |
| Database Links | Reactome: R-HSA-112409Reactome: R-HSA-5675221Reactome: R-HSA-9652817 |
| Cellular Localisation | CytoplasmNucleus |
| Alternative Antibody Names | Anti-Dual Specificity Protein Phosphatase 8 antibodyAnti-Dual Specificity Protein Phosphatase Hvh-5 antibodyAnti-DUSP8 antibodyAnti-C11orf81 antibodyAnti-VH5 antibody |
Information sourced from Uniprot.org
