Anti-DTNA antibody (STJA0037485)

SKU:
STJA0037485
£133.50 - £281.50
Processing The item has been added

Host: Rabbit
Applications: WB/IHC-F/IHC-P/ICC/IF/FC
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Rabbit monoclonal anti-DTNA for use in WB, IHC-F, IHC-P, ICC, IF and FC in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents.
Clonality : Monoclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in 50mM Tris-Glycine (pH 7.4) , 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA.
Purification: Affinity Purified
Dilution Range: WB-1:1000-1:5000
IHC-P-1:50-1:100
ICC/IF-1:100-1:200
FC-1:50-1:100
Storage Instruction: Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles.
Gene Symbol: DTNA
Gene ID: 1837
Uniprot ID: DTNA_HUMAN
Immunogen: Peptide
Tissue Specificity Highly expressed in brain, skeletal and cardiac muscles, and expressed at lower levels in lung, liver and pancreas. Isoform 2 is not expressed in cardiac muscle. Isoform 7 and isoform 8 are only expressed in muscle.
Post Translational Modifications Phosphorylation of DTN-1 on tyrosine kinase substrate domain present in the C-terminus.
Function May be involved in the formation and stability of synapses as well as being involved in the clustering of nicotinic acetylcholine receptors.
Protein Name Dystrobrevin Alpha
Dtn-A
Alpha-Dystrobrevin
Dystrophin-Related Protein 3
Database Links Reactome: R-HSA-9913351
Cellular Localisation Cytoplasm
Synapse
Cell Membrane
In Peripheral Nerves
Colocalizes With Magee1 In The Schwann Cell Membrane
Alternative Antibody Names Anti-Dystrobrevin Alpha antibody
Anti-Dtn-A antibody
Anti-Alpha-Dystrobrevin antibody
Anti-Dystrophin-Related Protein 3 antibody
Anti-DTNA antibody
Anti-DRP3 antibody

Information sourced from Uniprot.org