Anti-DSPP antibody (16-230) (STJ11105632)

Name: Anti-DSPP antibody (16-230) (STJ11105632)
SKU: STJ11105632
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⇓ Datasheet ⇓ SDS

SPECIFICATIONS

ClonalityPolyclonal

HostRabbit

ConjugationUnconjugated

IsotypeIgG

STJ11105632

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Short Description	Rabbit polyclonal Dentin Sialophosphoprotein Cleaved Into-Dentin Phosphoprotein (16-230) antibody for use in WB, IF, ICC and ELISA in human samples. Datasheet included with dilution recommendations, and related reagents.
Applications	WB/IF/ICC/ELISA
Host	Rabbit
Reactivity	Human
Note	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Clonality	Polyclonal
Isotype	IgG
Conjugation	Unconjugated
Concentration	Lot specific
Purification	Affinity purification
Dilution Range	WB:1:500-1:1000 IF/ICC:1:50-1:200 ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Formulation	PBS with 0.05% Proclin300, 50% Glycerol, pH 7.3.
Storage Instruction	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol	DSPP
Gene ID	1834
Uniprot ID	DSPP_HUMAN
Immunogen Region	16-230
Immunogen Sequence	IPVPQSKPLERHVEKSMNLH LLARSNVSVQDELNASGTIK ESGVLVHEGDRGRQENTQDG HKGEGNGSKWAEVGGKSFST YSTLANEEGNIEGWNGDTGK AETYGHDGIHGKEENITANG IQGQVSIIDNAGATNRSNTN GNTDKNTQNGDVGDAGHNED VAVVQEDGPQVAGSNNSTDN EDEIIENSCRNEGNTSEITP QINSKRNGTKEAEVT
Specificity	Recombinant Protein corresponding to a sequence within amino acids 16-230 of human DSPP (NP_055023.2).

Tissue Specificity	Expressed in teeth. DPP is synthesized by odontoblast and transiently expressed by pre-ameloblasts.
Post Translational Modifications	DSP is glycosylated.
Function	DSP may be an important factor in dentinogenesis. DPP may bind high amount of calcium and facilitate initial mineralization of dentin matrix collagen as well as regulate the size and shape of the crystals.
Protein Name	Dentin Sialophosphoprotein Cleaved Into - Dentin Phosphoprotein Dentin Phosphophoryn Dpp - Dentin Sialoprotein Dsp
Database Links	Reactome: R-HSA-3000178
Cellular Localisation	Secreted Extracellular Space Extracellular Matrix
Alternative Antibody Names	Anti-Dentin Sialophosphoprotein Cleaved Into - Dentin Phosphoprotein antibody Anti-Dentin Phosphophoryn antibody Anti-Dpp - Dentin Sialoprotein antibody Anti-Dsp antibody Anti-DSPP antibody

Information sourced from Uniprot.org