• Western blot analysis of the lysates from RAW264.7cells using DRD4 antibody.
  • Western blot analysis of lysates from MCF-7 and HUVEC cells, using DRD4 Antibody. The lane on the right is blocked with the synthesized peptide.
  • Western blot analysis of K562 cells using D4DR Polyclonal Antibody
  • Immunofluorescence analysis of MCF7 cells, using DRD4 Antibody. The picture on the right is blocked with the synthesized peptide.
  • Western blot analysis of various cells using D4DR Polyclonal Antibody

Anti-DRD4 antibody (355-404 aa) (STJ92643)

SKU:
STJ92643

£46.00 - £226.00
Current Stock:
Host: Rabbit
Applications: WB/IF/ELISA
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-D4 dopamine receptor dopamine receptor (355-404 aa) is suitable for use in Western Blot, Immunofluorescence and ELISA research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-1:2000
IF 1:200-1:1000
ELISA 1:40000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: DRD4
Gene ID: 1815
Uniprot ID: DRD4_HUMAN
Immunogen Region: 355-404 aa
Specificity: D4DR Polyclonal Antibody detects endogenous levels of D4DR protein.
Immunogen: The antiserum was produced against synthesized peptide derived from the human DRD4 at the amino acid range 355-404
Post Translational Modifications Polyubiquitinated by the BCR(KLHL12) E3 ubiquitin ligase complex: polyubiquitination does not lead to degradation of DRD4 protein. Palmitoylated. Palmitoylation of the C-terminal Cys is important for normal expression at the cell membrane.
Function Dopamine receptor responsible for neuronal signaling in the mesolimbic system of the brain, an area of the brain that regulates emotion and complex behavior. Activated by dopamine, but also by epinephrine and norepinephrine, and by numerous synthetic agonists and drugs. Agonist binding triggers signaling via G proteins that inhibit adenylyl cyclase. Modulates the circadian rhythm of contrast sensitivity by regulating the rhythmic expression of NPAS2 in the retinal ganglion cells.
Protein Name D(4 Dopamine Receptor
D(2c Dopamine Receptor
Dopamine D4 Receptor
Database Links Reactome: R-HSA-390651
Reactome: R-HSA-418594
Cellular Localisation Cell Membrane
Multi-Pass Membrane Protein
Alternative Antibody Names Anti-D(4 Dopamine Receptor antibody
Anti-D(2c Dopamine Receptor antibody
Anti-Dopamine D4 Receptor antibody
Anti-DRD4 antibody

Information sourced from Uniprot.org

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