Anti-DPP9 antibody (STJA0009792)

SKU:
STJA0009792

Current Stock:
Host: Rabbit
Applications: WB
Reactivity: Human/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Dipeptidyl peptidase 9 is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: DPP9
Gene ID: 91039
Uniprot ID: DPP9_HUMAN
Specificity: This antibody detects endogenous levels of DPP9 at Human, Mouse
Immunogen: Synthesized peptide derived from human DPP9
Function Dipeptidyl peptidase that cleaves off N-terminal dipeptides from proteins having a Pro or Ala residue at position 2. Acts as a key inhibitor of caspase-1-dependent monocyte and macrophage pyroptosis in resting cells by preventing activation of NLRP1 and CARD8. Sequesters the cleaved C-terminal part of NLRP1 and CARD8, which respectively constitute the active part of the NLRP1 and CARD8 inflammasomes, in a ternary complex, thereby preventing their oligomerization and activation. The dipeptidyl peptidase activity is required to suppress NLRP1 and CARD8.however, neither NLRP1 nor CARD8 are bona fide substrates of DPP9, suggesting the existence of substrate(s) required for NLRP1 and CARD8 inhibition.
Protein Name Dipeptidyl Peptidase 9
Dp9
Dipeptidyl Peptidase Iv-Related Protein 2
Dprp-2
Dipeptidyl Peptidase Ix
Dpp Ix
Dipeptidyl Peptidase-Like Protein 9
Dplp9
Cellular Localisation Isoform 1: Cytoplasm
Cytosol
Isoform 2: Nucleus
Alternative Antibody Names Anti-Dipeptidyl Peptidase 9 antibody
Anti-Dp9 antibody
Anti-Dipeptidyl Peptidase Iv-Related Protein 2 antibody
Anti-Dprp-2 antibody
Anti-Dipeptidyl Peptidase Ix antibody
Anti-Dpp Ix antibody
Anti-Dipeptidyl Peptidase-Like Protein 9 antibody
Anti-Dplp9 antibody
Anti-DPP9 antibody
Anti-DPRP2 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance