Anti-Dopamine Receptor D4 antibody (STJ500717)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthetic peptide corresponding to unique sequence on Dopamine Receptor D4 protein.
General Information
| Short Description | Rabbit polyclonal antibody anti-Dopamine Receptor D4 is suitable for use in Confocal Microscopy, ELISA, Immunocytochemistry, Immunofluorescence, Immunohistochemistry and Western Blot research applications. |
| Applications | CM/ELISA/ICC/IF/IHC/WB |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 0.5-1.5 ยตg/ยตl |
| Purification | Affinity Purified |
| Dilution Range | WB: 1:1, 000-1:1, 5000DB: 1:50, 000ELISA: 1:50, 000IP: 1:200IHC: 1:250ICC: 1:250IF: 1:250CFM: 1:250 |
| Formulation | Contains Tris, HCl/Glycine buffer pH 7.4-7.8, 30% Glycerol and 0.5% BSA, along with cryo-protective agents, Hepes, and long-term preservatives (0.02% Sodium Azide). |
| Storage Instruction | Store at-20ยฐC for long term storage. Avoid freeze-thaw cycles. |
Target Information
| Gene Symbol | Drd4 |
| Gene ID | 13491 |
| Uniprot ID | DRD4_MOUSE |
| Immunogen | Synthetic peptide corresponding to unique sequence on Dopamine Receptor D4 protein. |
Additional Info
| Tissue Specificity | Detected in olfactory bulb, hypothalamus, olfactory tubercle, brainstem and striatum. |
| Post Translational Modifications | Palmitoylated. Palmitoylation of the C-terminal Cys is important for normal expression at the cell membrane. |
| Function | Dopamine receptor responsible for neuronal signaling in the mesolimbic system of the brain, an area of the brain that regulates emotion and complex behavior. Activated by dopamine, but also by epinephrine and norepinephrine, and by numerous synthetic agonists and drugs. Agonist binding triggers signaling via G proteins that inhibit adenylyl cyclase. Modulates the circadian rhythm of contrast sensitivity by regulating the rhythmic expression of NPAS2 in the retinal ganglion cells. |
| Protein Name | D(4 Dopamine ReceptorD(2c Dopamine ReceptorDopamine D4 Receptor |
| Database Links | Reactome: R-MMU-390651Reactome: -MMU-418594 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-D(4 Dopamine Receptor antibodyAnti-D(2c Dopamine Receptor antibodyAnti-Dopamine D4 Receptor antibodyAnti-Drd4 antibody |
Information sourced from Uniprot.org