• Western blot analysis of lysates from HepG2 cells, using DOK3 Antibody. The lane on the right is blocked with the synthesized peptide.
  • Western blot analysis of the lysates from K562 cells using DOK3 antibody.
  • Western blot analysis of various cells using Dok-3 Polyclonal Antibody

Anti-DOK3 antibody (101-150 aa) (STJ92762)

SKU:
STJ92762

£46.00 - £226.00
Current Stock:
Host: Rabbit
Applications: WB/IHC/IF/ELISA
Reactivity: Human/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Docking protein 3 (101-150 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-1:2000
IHC 1:100-1:300
IF 1:200-1:1000
ELISA 1:20000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: DOK3
Gene ID: 79930
Uniprot ID: DOK3_HUMAN
Immunogen Region: 101-150 aa
Specificity: Dok-3 Polyclonal Antibody detects endogenous levels of Dok-3 protein.
Immunogen: The antiserum was produced against synthesized peptide derived from the human DOK3 at the amino acid range 101-150
Post Translational Modifications Constitutively tyrosine-phosphorylated. On IL2 stimulation, phosphorylated on C-terminal tyrosine residues possibly by Src kinases. Can also be phosphorylated by ABL1 kinase.
Function DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK3 is a negative regulator of JNK signaling in B-cells through interaction with INPP5D/SHIP1. May modulate ABL1 function.
Protein Name Docking Protein 3
Downstream Of Tyrosine Kinase 3
Database Links Reactome: R-HSA-6798695
Cellular Localisation Cytoplasm
Cell Membrane
Peripheral Membrane Protein
Cytoplasmic Side
Alternative Antibody Names Anti-Docking Protein 3 antibody
Anti-Downstream Of Tyrosine Kinase 3 antibody
Anti-DOK3 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance