• Anti-DOG1 antibody [SP31] (STJ16101447)

Anti-DOG1 antibody [SP31] (STJ16101447)

SKU:
STJ16101447-1

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Host: Rabbit
Applications: IHC-P
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit monoclonal antibody anti-DOG1 is suitable for use in Immunohistochemistry research applications.
Clonality: Monoclonal
Clone ID: SP31
Conjugation: Unconjugated
Isotype: IgG
Formulation: Tris Buffer, pH 7.3-7.7, containing 1% BSA and <0.1% Sodium Azide
Dilution Range: IHC-P 1:100-1:500
Storage Instruction: Store at 2-8°C upon receipt.
Background DOG1 is a calcium-dependent chloride channel protein that is encoded by a gene called TMEM16A (TMEM16 FLJ10261, ANO1, ORAOV2, and AOS2) located on chromosome 11q13. DOG1 has many significant functions such as regulation of the cholinergic activity of gastrointestinal smooth muscle 2 and regulation of both the survival and proliferation of cells. Anti-DOG1 antibody has been shown to be useful in the identification of gastrointestinal stromal tumors (GIST).

Information sourced from Uniprot.org

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