Anti-DOC2B antibody (360-412) {Biotin} (STJ500787)

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STJ500787-100
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Short Description :Rabbit polyclonal antibody anti-DOC2B (360-412) is suitable for use in ELISA, Immunohistochemistry, Immunoprecipitation and Western Blot research applications.
Applications:ELISA/IHC/IP/WB
Host:Rabbit
Reactivity:Human/Monkey/Mouse/Rat
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality :Polyclonal
Isotype:IgG
Conjugation:Biotin
Concentration:0.61 µg/µl
Purification:Affinity Purified
Dilution Range:WB: 1:500
DB: 1:10, 000
ELISA: 1:10, 000
IP: 1:200
IHC: 1:50-1:100
Formulation:Contains Tris, HCl/Glycine buffer pH 7.4-7.8, 30% Glycerol and 0.5% BSA, along with cryo-protective agents, Hepes, and long-term preservatives (0.02% Sodium Azide).
Storage Instruction:Store at-20°C for long term storage. Avoid freeze-thaw cycles.
Gene Symbol:Doc2b
Gene ID:81820
Uniprot ID:DOC2B_RAT
Immunogen:Synthetic Peptide taken within amino acid region 360-412 on DOC2b gene.
Immunogen Region:360-412
Tissue Specificity Expressed in brain.highly enriched in neurons.
Function Calcium sensor which positively regulates SNARE-dependent fusion of vesicles with membranes. Binds phospholipids in a calcium-dependent manner and may act at the priming stage of fusion by modifying membrane curvature to stimulate fusion. Involved in calcium-triggered exocytosis in chromaffin cells and calcium-dependent spontaneous release of neurotransmitter in absence of action potentials in neuronal cells. Involved both in glucose-stimulated insulin secretion in pancreatic cells and insulin-dependent GLUT4 transport to the plasma membrane in adipocytes.
Protein Name Double C2-Like Domain-Containing Protein Beta
Doc2-Beta
Cellular Localisation Cytoplasm
Cytoplasmic Granule
Cell Membrane
Peripheral Membrane Protein
Translocates To The Plasma Membrane In A Calcium-Dependent Manner
Alternative Antibody Names Anti-Double C2-Like Domain-Containing Protein Beta antibody
Anti-Doc2-Beta antibody
Anti-Doc2b antibody

Information sourced from Uniprot.org

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