• Western blot analysis of lysates from Jurkat and K562 cells, using RCL Antibody. The lane on the right is blocked with the synthesized peptide.
  • Western blot analysis of the lysates from 293 cells using RCL antibody.
  • Western blot analysis of various cells using RCL Polyclonal Antibody

Anti-DNPH1 antibody (1-50 aa) (STJ95397)

SKU:
STJ95397

£48.00 - £252.00
Current Stock:
Host: Rabbit
Applications: WB/IHC
Reactivity: Human/Rat/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-2 deoxynucleoside 5 phosphate N-hydrolase 1 (1-50 aa) is suitable for use in Western Blot and Immunohistochemistry research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-2000
IHC-P 1:50-300
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: DNPH1
Gene ID: 10591
Uniprot ID: DNPH1_HUMAN
Immunogen Region: 1-50 aa
Specificity: RCL Polyclonal Antibody detects endogenous levels of RCL protein.
Immunogen: The antiserum was produced against synthesized peptide derived from the human RCL at the amino acid range 1-50
Function Part of a nucleotide salvage pathway that eliminates epigenetically modified 5-hydroxymethyl-dCMP (hmdCMP) in a two-step process entailing deamination to cytotoxic 5-hydroxymethyl-dUMP (hmdUMP), followed by its hydrolysis into 5-hydroxymethyluracil (hmU) and 2-deoxy-D-ribose 5-phosphate (deoxyribosephosphate). Catalyzes the second step in that pathway, the hydrolysis of the N-glycosidic bond in hmdUMP, degrading this cytotoxic nucleotide to avoid its genomic integration.
Protein Name 5-Hydroxymethyl-Dump N-Hydrolase
2'-Deoxynucleoside 5'-Phosphate N-Hydrolase 1
C-Myc-Responsive Protein Rcl
Database Links Reactome: R-HSA-74259
Cellular Localisation Cytoplasm
Nucleus
Alternative Antibody Names Anti-5-Hydroxymethyl-Dump N-Hydrolase antibody
Anti-2'-Deoxynucleoside 5'-Phosphate N-Hydrolase 1 antibody
Anti-C-Myc-Responsive Protein Rcl antibody
Anti-DNPH1 antibody
Anti-C6orf108 antibody
Anti-RCL antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance