| Host: |
Rabbit |
| Applications: |
WB/ELISA |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-DnaJ homolog subfamily B member 6 (260-340 aa) is suitable for use in Western Blot and ELISA research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:500-2000ELISA 1:5000-20000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
DNAJB6 |
| Gene ID: |
10049 |
| Uniprot ID: |
DNJB6_HUMAN |
| Immunogen Region: |
260-340 aa |
| Specificity: |
DNJB6 Polyclonal Antibody detects endogenous levels of protein. |
| Immunogen: |
Synthesized peptide derived from the human protein at the amino acid range 260-340 |
| Function | Has a stimulatory effect on the ATPase activity of HSP70 in a dose-dependent and time-dependent manner and hence acts as a co-chaperone of HSP70. Plays an indispensable role in the organization of KRT8/KRT18 filaments. Acts as an endogenous molecular chaperone for neuronal proteins including huntingtin. Suppresses aggregation and toxicity of polyglutamine-containing, aggregation-prone proteins. Also reduces cellular toxicity and caspase-3 activity. Isoform B: Isoform B but not isoform A inhibits huntingtin aggregation. |
| Protein Name | Dnaj Homolog Subfamily B Member 6Hhdj1Heat Shock Protein J2Hsj-2MrjMsj-1 |
| Database Links | Reactome: R-HSA-3371453 |
| Cellular Localisation | CytoplasmPerinuclear RegionNucleusMyofibrilSarcomereZ Line |
| Alternative Antibody Names | Anti-Dnaj Homolog Subfamily B Member 6 antibodyAnti-Hhdj1 antibodyAnti-Heat Shock Protein J2 antibodyAnti-Hsj-2 antibodyAnti-Mrj antibodyAnti-Msj-1 antibodyAnti-DNAJB6 antibodyAnti-HSJ2 antibodyAnti-MRJ antibodyAnti-MSJ1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
