| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | DIDO1 |
| Gene ID: | 11083 |
| Uniprot ID: | DIDO1_HUMAN |
| Immunogen Region: | 1-300 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human DIDO1 (NP_071388.2). |
| Immunogen Sequence: | MDDKGDPSNEEAPKAIKPTS KEFRKTWGFRRTTIAKREGA GDAEADPLEPPPPQQQLGLS LRRSGRQPKRTERVEQFLTI ARRRGRRSMPVSLEDSGEPT SCPATDAETASEGSVESASE TRSGPQSASTAVKERPASSE KVKGGDDHDDTSDSDSDGLT LKELQNRLRRKREQEPTERP LKGIQSRLRKKRREEGPAET VGSEASDTVEGVLPSKQEPE NDQGVVSQAGKDDRESKLE |
| Tissue Specificity | Ubiquitous. |
| Function | Putative transcription factor, weakly pro-apoptotic when overexpressed. Tumor suppressor. Required for early embryonic stem cell development. Isoform 2: Displaces isoform 4 at the onset of differentiation, required for repression of stemness genes. |
| Protein Name | Death-Inducer Obliterator 1Dio-1Hdido1Death-Associated Transcription Factor 1Datf-1 |
| Database Links | Reactome: R-HSA-1221632 Q9BTC0-1 |
| Cellular Localisation | CytoplasmNucleusCytoskeletonSpindleTranslocates To The Nucleus After Pro-Apoptotic StimuliTranslocates To The Mitotic Spindle Upon Loss Of Interaction With H3k4me3 During Early Mitosis |
| Alternative Antibody Names | Anti-Death-Inducer Obliterator 1 antibodyAnti-Dio-1 antibodyAnti-Hdido1 antibodyAnti-Death-Associated Transcription Factor 1 antibodyAnti-Datf-1 antibodyAnti-DIDO1 antibodyAnti-C20orf158 antibodyAnti-DATF1 antibodyAnti-KIAA0333 antibody |
Information sourced from Uniprot.org