Host: |
Rabbit |
Applications: |
WB |
Reactivity: |
Human |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit polyclonal antibody anti-DIDO1 (1-300) is suitable for use in Western Blot research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
Purification: |
Affinity purification |
Dilution Range: |
WB 1:500-1:2000 |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
DIDO1 |
Gene ID: |
11083 |
Uniprot ID: |
DIDO1_HUMAN |
Immunogen Region: |
1-300 |
Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human DIDO1 (NP_071388.2). |
Immunogen Sequence: |
MDDKGDPSNEEAPKAIKPTS KEFRKTWGFRRTTIAKREGA GDAEADPLEPPPPQQQLGLS LRRSGRQPKRTERVEQFLTI ARRRGRRSMPVSLEDSGEPT SCPATDAETASEGSVESASE TRSGPQSASTAVKERPASSE KVKGGDDHDDTSDSDSDGLT LKELQNRLRRKREQEPTERP LKGIQSRLRKKRREEGPAET VGSEASDTVEGVLPSKQEPE NDQGVVSQAGKDDRESKLE |
Tissue Specificity | Ubiquitous. |
Function | Putative transcription factor, weakly pro-apoptotic when overexpressed. Tumor suppressor. Required for early embryonic stem cell development. Isoform 2: Displaces isoform 4 at the onset of differentiation, required for repression of stemness genes. |
Protein Name | Death-Inducer Obliterator 1Dio-1Hdido1Death-Associated Transcription Factor 1Datf-1 |
Database Links | Reactome: R-HSA-1221632 Q9BTC0-1 |
Cellular Localisation | CytoplasmNucleusCytoskeletonSpindleTranslocates To The Nucleus After Pro-Apoptotic StimuliTranslocates To The Mitotic Spindle Upon Loss Of Interaction With H3k4me3 During Early Mitosis |
Alternative Antibody Names | Anti-Death-Inducer Obliterator 1 antibodyAnti-Dio-1 antibodyAnti-Hdido1 antibodyAnti-Death-Associated Transcription Factor 1 antibodyAnti-Datf-1 antibodyAnti-DIDO1 antibodyAnti-C20orf158 antibodyAnti-DATF1 antibodyAnti-KIAA0333 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance