Anti-DHX30 antibody (336-501) (STJ11105560)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal Atp-Dependent Rna Helicase Dhx30 (336-501) antibody for use in WB and ELISA in human and mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:1000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | DHX30 |
| Gene ID | 22907 |
| Uniprot ID | DHX30_HUMAN |
| Immunogen Region | 336-501 |
| Immunogen Sequence | RELGETQRRPCTIQVPEPIL RKIETFLNHYPVESSWIAPE LRLQSDDILPLGKDSGPLSD PITGKPYVPLLEAEEVRLSQ SLLELWRRRGPVWQEAPQLP VDPHRDTILNAIEQHPVVVI SGDTGCGKTTRIPQLLLERY VTEGRGARCNVIITQPRRIS AVSVAQ |
| Specificity | Recombinant Protein corresponding to a sequence within amino acids 336-501 of human DHX30 (NP_619520.1). |
Additional Info
| Post Translational Modifications | Isoform 2: Phosphorylated on Ser-15. |
| Function | RNA-dependent helicase. Plays an important role in the assembly of the mitochondrial large ribosomal subunit. Required for optimal function of the zinc-finger antiviral protein ZC3HAV1. Associates with mitochondrial DNA. Involved in nervous system development and differentiation through its involvement in the up-regulation of a number of genes which are required for neurogenesis, including GSC, NCAM1, neurogenin, and NEUROD. |
| Protein Name | Atp-Dependent Rna Helicase Dhx30Deah Box Protein 30 |
| Database Links | |
| Cellular Localisation | CytoplasmMitochondrionMitochondrion MatrixMitochondrion NucleoidLocalizes To Mitochondrial Rna Granules Found In Close Proximity To The Mitochondrial NucleoidsRelocalizes To Stress Granules Upon Heat Stress |
| Alternative Antibody Names | Anti-Atp-Dependent Rna Helicase Dhx30 antibodyAnti-Deah Box Protein 30 antibodyAnti-DHX30 antibodyAnti-DDX30 antibodyAnti-KIAA0890 antibody |
Information sourced from Uniprot.org