| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-DGCR6L (1-220) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
DGCR6L |
| Gene ID: |
85359 |
| Uniprot ID: |
DGC6L_HUMAN |
| Immunogen Region: |
1-220 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-220 of human DGCR6L (NP_150282.2). |
| Immunogen Sequence: |
MERYAAALEEVADGARQQER HYQLLSALQSLVKELPSSFQ QRLSYTTLSDLALALLDGTV FEIVQGLLEIQHLTEKSLYN QRLRLQNEHRVLRQALRQKH QEAQQACRPHNLPVVQAAQQ RELEAVEHRIREEQRAMDQK IILELDRKVADQQSTLEKAG VAGFYVTTNPQELMLQMNLL ELIRKLQQRGCRAGNAALGL GGPWQSPAAQCDQKGSPVPP |
| Tissue Specificity | Widely expressed in fetal and adult tissues. Highest expression in liver, heart and skeletal muscle. Lower levels in pancreas and placenta. Weak expression in brain. |
| Function | May play a role in neural crest cell migration into the third and fourth pharyngeal pouches. |
| Protein Name | Protein Dgcr6lDigeorge Syndrome Critical Region 6-Like Protein |
| Cellular Localisation | NucleusPredominantly Nuclear |
| Alternative Antibody Names | Anti-Protein Dgcr6l antibodyAnti-Digeorge Syndrome Critical Region 6-Like Protein antibodyAnti-DGCR6L antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
![Western blot analysis of lysates from wild type (WT) and Emerin/Emerin/EMD knockout (KO) 293T cells, using [KO Validated] Emerin/EMD Rabbit polyclonal antibody (STJ119989) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 1s.](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/300x300/products/98774/382822/STJ119989_1__22320.1713151321.jpg?c=1 "Western blot analysis of lysates from wild type (WT) and Emerin/Emerin/EMD knockout (KO) 293T cells, using [KO Validated] Emerin/EMD Rabbit polyclonal antibody (STJ119989) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 1s.")