Anti-DEK antibody (51-200) [S8MR] (STJ11102678)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit monoclonal DEK (51-200) antibody for use in WB, IHC-P, IF, ICC and ELISA in human and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC-P/IF/ICC/ELISA |
| Host | Rabbit |
| Reactivity | Human/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | S8MR |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:1000IHC-P:1:50-1:200IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 0.05% BSA, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | DEK |
| Gene ID | 7913 |
| Uniprot ID | DEK_HUMAN |
| Immunogen Region | 51-200 |
| Immunogen Sequence | SLIVEGKREKKKVERLTMQV SSLQREPFTIAQGKGQKLCE IERIHFFLSKKKTDELRNLH KLLYNRPGTVSSLKKNVGQF SGFPFEKGSVQYKKKEEMLK KFRNAMLKSICEVLDLERSG VNSELVKRILNFLMHPKPSG KPLPKSKKTC |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 51-200 of human DEK (P35659). |
Additional Info
| Tissue Specificity | Ubiquitous. Expressed at relatively high levels. |
| Post Translational Modifications | Phosphorylated by CK2. Phosphorylation fluctuates during the cell cycle with a moderate peak during G(1) phase, and weakens the binding of DEK to DNA. |
| Function | Involved in chromatin organization. |
| Protein Name | Protein Dek |
| Database Links | Reactome: R-HSA-5250924Reactome: R-HSA-8864260Reactome: R-HSA-9616222 |
| Cellular Localisation | NucleusEnriched In Regions Where Chromatin Is Decondensed Or Sparse In The Interphase Nuclei |
| Alternative Antibody Names | Anti-Protein Dek antibodyAnti-DEK antibody |
Information sourced from Uniprot.org