Anti-DAZL antibody (200-295) (STJ115905)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal DAZL (200-295) antibody for use in WB, IHC-P, IF, ICC and ELISA in mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC-P/IF/ICC/ELISA |
| Host | Rabbit |
| Reactivity | Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:1000IHC-P:1:50-1:200IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.05% Proclin300, 50% Glycerol, pH7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | DAZL |
| Gene ID | 1618 |
| Uniprot ID | DAZL_HUMAN |
| Immunogen Region | 200-295 |
| Immunogen Sequence | QRSYVVPPAYSAVNYHCNEV DPGAEVVPNECSVHEATPPS GNGPQKKSVDR |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 200-250 of human DAZL (NP_001342.2). |
Additional Info
| Tissue Specificity | Testis specific. |
| Function | RNA-binding protein, which is essential for gametogenesis in both males and females. Plays a central role during spermatogenesis. Acts by binding to the 3'-UTR of mRNA, specifically recognizing GUU triplets, and thereby regulating the translation of key transcripts. |
| Protein Name | Deleted In Azoospermia-LikeDaz HomologDaz-Like AutosomalDeleted In Azoospermia-Like 1Spgy-Like-Autosomal |
| Database Links | |
| Cellular Localisation | CytoplasmNucleusPredominantly CytoplasmicNuclear In Spermatogonia Until Near The End Of The Meiotic Prophase And Cytoplasmic Localization From Then Onward |
| Alternative Antibody Names | Anti-Deleted In Azoospermia-Like antibodyAnti-Daz Homolog antibodyAnti-Daz-Like Autosomal antibodyAnti-Deleted In Azoospermia-Like 1 antibodyAnti-Spgy-Like-Autosomal antibodyAnti-DAZL antibodyAnti-DAZH antibodyAnti-DAZL1 antibodyAnti-DAZLA antibodyAnti-SPGYLA antibody |
Information sourced from Uniprot.org