• Immunofluorescence analysis of HUVEC cells, using CLTR1 Antibody. The picture on the right is blocked with the synthesized peptide.
  • Western blot analysis of lysates from COS7 cells, using CLTR1 Antibody. The lane on the right is blocked with the synthesized peptide.
  • Western blot analysis of COS-7 cells using CysLTR1 Polyclonal Antibody

Anti-CYSLTR1 antibody (131-180 aa) (STJ92609)

SKU:
STJ92609

Current Stock:
Host: Rabbit
Applications: WB/IHC/IF/ELISA
Reactivity: Human/Monkey
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Cysteinyl leukotriene receptor 1 (131-180 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-1:2000
IHC 1:100-1:300
IF 1:200-1:1000
ELISA 1:10000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: CYSLTR1
Gene ID: 10800
Uniprot ID: CLTR1_HUMAN
Immunogen Region: 131-180 aa
Specificity: CysLTR1 Polyclonal Antibody detects endogenous levels of CysLTR1 protein.
Immunogen: The antiserum was produced against synthesized peptide derived from the human CLTR1 at the amino acid range 131-180
Function Receptor for cysteinyl leukotrienes mediating bronchoconstriction of individuals with and without asthma. Stimulation by LTD4 results in the contraction and proliferation of smooth muscle, edema, eosinophil migration and damage to the mucus layer in the lung. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. The rank order of affinities for the leukotrienes is LTD4 >> LTE4 = LTC4 >> LTB4.
Protein Name Cysteinyl Leukotriene Receptor 1
Cysltr1
Cysteinyl Leukotriene D4 Receptor
Ltd4 Receptor
G-Protein Coupled Receptor Hg55
Hmtmf81
Database Links Reactome: R-HSA-391906
Reactome: R-HSA-416476
Reactome: R-HSA-9664535
Reactome: R-HSA-9679191
Cellular Localisation Cell Membrane
Multi-Pass Membrane Protein
Alternative Antibody Names Anti-Cysteinyl Leukotriene Receptor 1 antibody
Anti-Cysltr1 antibody
Anti-Cysteinyl Leukotriene D4 Receptor antibody
Anti-Ltd4 Receptor antibody
Anti-G-Protein Coupled Receptor Hg55 antibody
Anti-Hmtmf81 antibody
Anti-CYSLTR1 antibody
Anti-CYSLT1 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance