• Human mantle cell lymphoma stained with anti-Cyclin D1 antibody using peroxidase-conjugate and DAB chromogen. Note the nuclear staining of lymphoma cells.

Anti-Cyclin D1 antibody (200-295aa) [ZM178] (STJ180503)

SKU:
STJ180503

£152.50 - £560.50
Shipping:
Free Shipping
Current Stock:
Host: Mouse
Applications: IHC-P
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Mouse monoclonal antibody anti-Cyclin D1 (200-295aa) is suitable for use in Immunohistochemistry research applications.
Clonality: Monoclonal
Clone ID: ZM178
Conjugation: Unconjugated
Isotype: IgG2a/Kappa
Formulation: Tris-HCI buffer containing stabilizing protein (BSA) and <0.1% ProClin
Purification: Affinity purified
Dilution Range: 1:100-200
Storage Instruction: Store at 2‐8°C for up to 24 months. Predilute: Ready to use, no reconstitution necessary. Concentrate: Use dilution range and appropriate lab‐standardized diluent. Stability after dilution: 7 days at 24°C, 3 months at 2‐8°C, 6months at ‐20°C.
Gene Symbol: CCNDBP1
Gene ID: 23582
Uniprot ID: CCDB1_HUMAN
Immunogen Region: 200-295aa
Specificity: Positive control: Mantle cell lymphoma
Immunogen: Synthetic peptide corresponding to residues within aa 200-295 of Cyclin D1
Tissue Specificity Ubiquitously expressed. Expression is down-regulated in a variety of tumor types including breast, colon, prostate and rectal tumors, and is up-regulated in certain hepatic carcinomas.
Post Translational Modifications Phosphorylated.
Function May negatively regulate cell cycle progression. May act at least in part via inhibition of the cyclin-D1/CDK4 complex, thereby preventing phosphorylation of RB1 and blocking E2F-dependent transcription.
Protein Name Cyclin-D1-Binding Protein 1
Grap2 And Cyclin-D-Interacting Protein
Human Homolog Of Maid
Cellular Localisation Cytoplasm
Nucleus
Alternative Antibody Names Anti-Cyclin-D1-Binding Protein 1 antibody
Anti-Grap2 And Cyclin-D-Interacting Protein antibody
Anti-Human Homolog Of Maid antibody
Anti-CCNDBP1 antibody
Anti-DIP1 antibody
Anti-GCIP antibody
Anti-HHM antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance